Chemical Name:acetophenetidin, N-(4-ethoxyphenyl)acetamide
Boiling point: 671.2°F (355.1°C)
Molar mass:179.219 g·mol−1
Melting point:134 °C (273 °F)
Appearence:odorless fine white crystalline solid with a lightly bitter taste
What is Phenacetin?
Phenacetin is a pain-relieving and fever-reducing drug.
Where Phenacetin come from?
Phenacetin is a member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group. It has a role as a non-narcotic analgesic, a peripheral nervous system drug and a cyclooxygenase 3 inhibitor. It is a member of acetamides and an aromatic ether. It derives from a N-phenylacetamide, a 4-ethoxyaniline and a paracetamol.
What are the Phenacetin fuction ?
1. Antipyretic and analgesic, used to treat fever, headache, neuralgia, etc. The
antipyretic effect is stronger than the analgesic effect.
2.Phenacetin's analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope.
How to use phenacetin ?
Phenacetin alone use is more toxic,often used in compound preparations
Controversy point of phenacetin
Some people think phenacetin is used to treat rheumatoid arthritis (subacute type).
Another view is phenacetin only has antipyretic and analgesic effects, but no anti-inflammatory and anti-rheumatic effects..
NOTE:Phenacetin should not be used long-term and frequently